Product Name: HOOK3 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: HOOK3 antibody can be used for the detection of HOOK3 by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunohistochemistry at 10 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 79 kDa Observed: 77 kDa
Immunogen: HOOK3 antibody was raised against a 19 amino acid peptide from near the amino terminus of human HOOK3.The immunogen is located within amino acids 210 – 260 of HOOK3.
Host Species: Rabbit
Purification: HOOK3 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 57103-68-1
Product: Relugolix
Buffer: HOOK3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: HOOK3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: hook microtubule-tethering protein 3, HK3, h-hook3, hHK3, FLJ31058, Protein Hook homolog 3
Accession NO.: NP_115786
Protein Ino: 14165274
Official Symbol: HOOK3
Geneid: 84376
Background: The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems; their more divergent C-terminal domains mediate binding to organelles (1,2). HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3). HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4).
PubMed ID:http://aac.asm.org/content/23/4/551.abstract
