Product Name: HNRNPD Antibody
Species Reactivity: Human
Tested Applications: IF, WB
Applications: For WB starting dilution is: 1:1000For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 38 kDa
Immunogen: This HNRNPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human HNRNPD.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1223405-08-0
Product: PD150606
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Heterogeneous nuclear ribonucleoprotein D0, hnRNP D0, AU-rich element RNA-binding protein 1, HNRNPD, AUF1, HNRPD
Accession NO.: Q14103
Protein Ino: 13124489
Official Symbol: HNRNPD
Geneid: 3184
Background: This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are nucleic acid binding proteins and they complex withheterogeneous nuclear RNA (hnRNA). These proteins are associatedwith pre-mRNAs in the nucleus and appear to influence pre-mRNAprocessing and other aspects of mRNA metabolism and transport.While all of the hnRNPs are present in the nucleus, some seem toshuttle between the nucleus and the cytoplasm. The hnRNP proteinshave distinct nucleic acid binding properties. The protein encodedby this gene has two repeats of quasi-RRM domains that bind toRNAs. It localizes to both the nucleus and the cytoplasm. Thisprotein is implicated in the regulation of mRNA stability.Alternative splicing of this gene results in four transcriptvariants.
PubMed ID:http://aac.asm.org/content/23/3/402.abstract
