Product Name: HNF4a (phospho Ser304) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:1000
User Note:
Predicted Molecular Weight: 52 kDa
Immunogen: HNF4a (Phospho-Ser304) antibody was raised against a peptide sequence around phosphorylation site of serine 304 (L-R-S (p) -Q-V) derived from Human HNF4α.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Physical State: Liquid
CAS NO.: 1798871-31-4
Product: Histone Acetyltransferase Inhibitor II
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: TCF, HNF4, MODY, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, HNF4alpha, HNRPA1, TCF, HNF4A
Accession NO.: NP_000448.3
Protein Ino: 31077205
Official Symbol: HNF4A
Geneid: 3172
Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.
PubMed ID:http://aac.asm.org/content/23/2/320.abstract
