Product Name: HNF1B Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 61 kDa
Immunogen: This HNF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 842-07-9
Product: N-563
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1, HNF1B, TCF2
Accession NO.: P35680
Protein Ino: 547664
Official Symbol: HNF1B
Geneid: 6928
Background: This gene encodes a member of the homeodomain-containingsuperfamily of transcription factors. The protein binds to DNA aseither a homodimer, or a heterodimer with the related proteinhepatocyte nuclear factor 1-alpha. The gene has been shown tofunction in nephron development, and regulates development of theembryonic pancreas. Mutations in this gene result in renal cystsand diabetes syndrome and noninsulin-dependent diabetes mellitus,and expression of this gene is altered in some types of cancer.Multiple transcript variants encoding different isoforms have beenfound for this gene.
PubMed ID:http://aac.asm.org/content/23/2/317.abstract
