Product Name: HMGA2 Antibody
Species Reactivity: Human
Tested Applications: Flow, WB
Applications: For WB starting dilution is: 1:1000For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 12 kDa
Immunogen: This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 101043-37-2
Product: CC122
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.39 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Accession NO.: P52926
Protein Ino: 1708263
Official Symbol: HMGA2
Geneid: 8091
Background: This gene encodes a protein that belongs to thenon-histone chromosomal high mobility group (HMG) protein family.HMG proteins function as architectural factors and are essentialcomponents of the enhancesome. This protein contains structuralDNA-binding domains and may act as a transcriptional regulatingfactor. Identification of the deletion, amplification, andrearrangement of this gene that are associated with myxoidliposarcoma suggests a role in adipogenesis and mesenchymaldifferentiation. A gene knock out study of the mouse counterpartdemonstrated that this gene is involved in diet-induced obesity.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
PubMed ID:http://aac.asm.org/content/23/1/67.abstract
