Product Name: HIG1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, ICC, IF, WB
Applications: HIG1 antibody can be used for detection of HIG1 by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: HIG1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HIG1.The immunogen is located within the first 50 amino acids of HIG1.
Host Species: Rabbit
Purification: HIG1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 923978-27-2
Product: Bavachin
Buffer: HIG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: HIG1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HIG1 Antibody: HIG1, RCF1a, HIG1, HSPC010, HIG1 domain family member 1A, mitochondrial, Hypoxia-inducible gene 1 protein
Accession NO.: NP_001093138
Protein Ino: 153085461
Official Symbol: HIGD1A
Geneid: 25994
Background: HIG1 Antibody: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG1 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.
PubMed ID:http://aac.asm.org/content/22/4/585.abstract
