Product Name: HERC3 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 117 kDa
Immunogen: This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 486-60-2
Product: ML364
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.25 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Probable E3 ubiquitin-protein ligase HERC3, 632-, HECT domain and RCC1-like domain-containing protein 3, HERC3, KIAA0032
Accession NO.: Q15034
Protein Ino: 2495699
Official Symbol: HERC3
Geneid: 8916
Background: HERC3 belongs to the HERC family of ubiquitin ligases, allof which contain a HECT domain and at least 1 RCC1 (MIM179710)-like domain (RLD). The 350-amino acid HECT domain ispredicted to catalyze the formation of a thioester with ubiquitinbefore transferring it to a substrate, and the RLD is predicted toact as a guanine nucleotide exchange factor for small G proteins(Hochrainer et al., 2005 [PubMed 15676274]).
PubMed ID:http://aac.asm.org/content/22/2/208.abstract
