Product Name: HBA2 Antibody
Species Reactivity: Human, Mouse
Tested Applications: Flow, IHC-P, WB
Applications: For FACS starting dilution is: 1:25For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 15 kDa
Immunogen: This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 56-59-7
Product: Coproporphyrin III
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
Accession NO.: P69905
Protein Ino: 57013850
Official Symbol: HBA1
Geneid: 3039, 3040
Background: HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta – pseudozeta – mu – pseudoalpha-1 – alpha-2 – alpha-1 – theta – 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
PubMed ID:http://aac.asm.org/content/21/2/341.abstract
