Product Name: HAT1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 50 kDa
Immunogen: This HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HAT1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1502816-23-0
Product: Glucagon
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1, HAT1, KAT1
Accession NO.: O14929
Protein Ino:
Official Symbol: HAT1
Geneid: 8520
Background: The protein encoded by this gene is a type B histoneacetyltransferase (HAT) that is involved in the rapid acetylationof newly synthesized cytoplasmic histones, which are in turnimported into the nucleus for de novo deposition onto nascent DNAchains. Histone acetylation, particularly of histone H4, plays animportant role in replication-dependent chromatin assembly.Specifically, this HAT can acetylate soluble but not nucleosomalhistone H4 at lysines 5 and 12, and to a lesser degree, histone H2Aat lysine 5. Alternatively spliced transcript variants have beenidentified for this gene.
PubMed ID:http://aac.asm.org/content/21/2/268.abstract
