Product Name: GZMB Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IHC-P
Applications: IHC-P (1:100)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: GZMB antibody was raised against amino acids from the C-Terminus of Granzyme B (Human)
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 2306-27-6
TMC353121
Buffer: 10 mM PBS, pH 7.4, BSA, with less than 0.1% sodium azide.
Concentration:
Storage Conditions: Store GZMB antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
Accession NO.: P10144
Protein Ino: 317373361
Official Symbol: GZMB
Geneid: 3002
Background: Granzyme A and granzyme B are serine proteases that mediate apoptotic signaling in cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. Both granzyme A and granzyme B are synthesized as inactive proenzymes, and they are stored within cytolytic granules and released by effector cells during degradation. This antibody should be useful for the localization of granzyme B-containing lytic granules and for the characterization of activated CTLs or NK cells.
PubMed ID:http://aac.asm.org/content/20/6/839.abstract
