Product Name: GRIP1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 118 kDa Observed: 115 kDa
Immunogen: Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1.The immunogen is located within the last 50 amino acids of GRIP1.
Host Species: Rabbit
Purification: GRIP1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1159600-41-5
Isavuconazole
Buffer: GRIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: GRIP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GRIP1 Antibody: GRIP, Glutamate receptor-interacting protein 1, GRIP-1
Accession NO.: NP_066973
Protein Ino: 223890252
Official Symbol: GRIP1
Geneid: 23426
Background: GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
PubMed ID:http://aac.asm.org/content/20/1/71.abstract
