Product Name: GRIA3 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 101 kDa
Immunogen: This GRIA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human GRIA3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 134-03-2
GSK461364
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3, GRIA3, GLUR3, GLURC
Accession NO.: P42263
Protein Ino: 77416864
Official Symbol: GRIA3
Geneid: 2892
Background: Glutamate receptors are the predominant excitatoryneurotransmitter receptors in the mammalian brain and are activatedin a variety of normal neurophysiologic processes. These receptorsare heteromeric protein complexes composed of multiple subunits,arranged to form ligand-gated ion channels. The classification ofglutamate receptors is based on their activation by differentpharmacologic agonists. The subunit encoded by this gene belongs toa family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate)-sensitive glutamate receptors, and is subject to RNAediting (AGA->GGA; R->G). Alternative splicing at this locusresults in different isoforms, which may vary in their signaltransduction properties.
PubMed ID:http://aac.asm.org/content/19/6/1073.abstract
