Product Name: Bmf Antibody [9G10]
Species Reactivity: Human, Mouse
Tested Applications: Flow, IP, WB
Applications: Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant mouse Bmf.
Host Species: Rat
Purification: >95% (SDS-PAGE)
Physical State: Liquid
CAS NO.: 15302-15-5
Product: Etosalamide
Buffer: Liquid. In PBS containing 0.02% sodium azide.
Concentration: 1 mg/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Bcl-2-modifying Factor
Accession NO.: NP_277038
Protein Ino: 15723378
Official Symbol: BMF
Geneid: 90427
Background: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
PubMed ID:http://aac.asm.org/content/42/4/734.abstract
