Product Name: Bloom Syndrome (phospho Ser527) Antibody
Species Reactivity: Human, Mouse, Non-human Primate, Rat
Tested Applications: ELISA, IHC, WB
Applications: ELISA, Western (immuno) blotting, Immunostaining (in testing)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: A synthetic peptide surrounding amino acid S527
Host Species: Rabbit
Purification: Affinity Purified
Physical State:
CAS NO.: 21498-08-8
Product: Lofexidine (hydrochloride)
Buffer:
Concentration:
Storage Conditions:
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Bloom Syndrome Protein pS527 phospho specific, BS, RECQ2, RECQL2, RECQL3
Accession NO.: AAI15031
Protein Ino: 1705486
Official Symbol: BLM
Geneid: 641
Background: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Blooms syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Blooms syndrome, namely cancer and diabetes.
PubMed ID:http://aac.asm.org/content/42/3/654.abstract
