Product Name: Bim Antibody [1C2H4]
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, IF, WB
Applications: Bim antibody can be used for detection of Bim by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Host Species: Mouse
Purification: Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Physical State: Liquid
CAS NO.: 28300-74-5
Product: Antimonyl (potassium tartrate trihydrate)
Buffer: Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Bim monoclonal antibody can be stored at -20˚C, stable for one year.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Bim Antibody [1C2H4] : BAM, BIM, BOD
Accession NO.: NP_619527
Protein Ino: 20336315
Official Symbol: BCL2L11
Geneid: 10018
Background: Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
PubMed ID:http://aac.asm.org/content/42/2/440.abstract
