Product Name: BMP1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC
Applications: BMP1 antibody can be used in ELISA starting at 1:10000 – 1:50000, Western Blot starting at 1:500 – 1:2000, immunohistochemistry starting at 2.5 μg/mL, and immunofluorescence.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: BMP1 antibody was raised against amino acids 372-986 of BMP1 (Human).
Host Species: Rabbit
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 4491-19-4
Product: Indaconitine
Buffer: PBS, 0.09% sodium azide.
Concentration:
Storage Conditions: Antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BMP1, Bone morphogenetic protein 1, OI13, PCP-2, Procollagen C-proteinase-2, Procollagen C-proteinase, MTld, PCOLC, PCP-1, Procollagen C-endopeptidase, TLD, BMP-1, Mammalian tolloid, Mammalian tolloid protein, PCP
Accession NO.: P13497
Protein Ino: 13124688
Official Symbol: BMP1
Geneid: 649
Background: BMP1 encodes a Metallopeptidase M12A type protease that is comprised of an amino terminal signal peptide, prodomain and an astacin-like protease domain followed by CUB and EGF-like motifs. BMP1 protein has been shown to cleave chordin, the C-terminal propeptides of procollagen I, II, III and VII, pro-lysyl oxidase, probiglycan, and laminin-5, and its expression has been shown to induce cartilage and bone formation in vivo. At least six spliced variants have been reported. These share the N-terminal protease domain but differ in the C-terminus, and thus contain varying numbers of CUB and EGF-like domains.
PubMed ID:http://aac.asm.org/content/42/4/951.abstract
