Product Name: BCL-2 (phospho Ser87) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 28 kDa
Immunogen: BCL-2 (phospho Ser87) antibody was raised against a peptide sequence around phosphorylation site of serine 87 (A-L-S (p)-P-V) derived from Human BCL-2.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 51-79-6
Product: Urethane
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Apoptosis regulator Bcl-2, BCL2
Accession NO.: NP_000624.2
Protein Ino: 72198189
Official Symbol: BCL2
Geneid: 596
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
PubMed ID:http://aac.asm.org/content/53/11/4915.abstract
