Product Name: BCL 2 (Ab 56) Antibody
Species Reactivity: Human
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 26 kDa
Immunogen: BCL-2 (Ab-56) antibody was raised against a peptide sequence around aa. 54~58 (G-H-T-P-H) derived from Human BCL-2.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 5466-77-3
Product: Octinoxate
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Bcl-2, PPP1R50, OIP3, PK2, PK3, PKM2, BCL2
Accession NO.: NP_000624.2
Protein Ino: 72198189
Official Symbol: BCL2
Geneid: 596
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
PubMed ID:http://aac.asm.org/content/53/11/4934.abstract
