Product Name: BCL6 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: BCL6 antibody can be used for detection of BCL6 by Western blot at 1 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 78 kDa
Immunogen: BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.The immunogen is located within amino acids 370 – 420 of BCL6.
Host Species: Rabbit
Purification: BCL6 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 471-66-9
Product: alpha-Boswellic acid
Buffer: BCL6 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BCL6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BCL6 Antibody: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27, BCL5, B-cell lymphoma 6 protein, B-cell lymphoma 5 protein, BCL-6
Accession NO.: NP_001124317
Protein Ino: 195927002
Official Symbol: BCL6
Geneid: 604
Background: BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).
PubMed ID:http://aac.asm.org/content/53/12/4999.abstract
