Product Name: BCL3 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: BCL3 antibody can be used for detection of BCL3 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 50 kDa
Immunogen: Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.The immunogen is located within amino acids 360 – 410 of BCL3.
Host Species: Rabbit
Purification: BCL3 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 58-86-6
Product: Xylose
Buffer: BCL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BCL3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BCL3 Antibody: BCL4, D19S37, BCL4, B-cell lymphoma 3 protein, Proto-oncogene BCL3, BCL-3
Accession NO.: NP_005169
Protein Ino: 164664508
Official Symbol: BCL3
Geneid: 602
Background: BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ-B proteins. The expression of this gene can be induced by NF-κ-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
PubMed ID:http://aac.asm.org/content/53/12/4987.abstract
