Product Name: BCHE Antibody
Species Reactivity: Dog, Human, Mouse
Tested Applications: ELISA, IHC, WB
Applications: BCHE antibody can be used for detection of BCHE by ELISA at 1:312500. BCHE antibody can be used for detection of BCHE by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 68 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCHE.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 52-49-3
Product: Trihexyphenidyl (hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store BCHE antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BCHE, CHE1, E1, CHE2
Accession NO.: NP_000046
Protein Ino: 4557351
Official Symbol: BCHE
Geneid: 590
Background: Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
PubMed ID:http://aac.asm.org/content/53/11/4816.abstract
