Product Name: BAMBI Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: BAMBI antibody can be used for detection of BAMBI by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 29 kDa Observed: 26 kDa
Immunogen: BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI.The immunogen is located within amino acids 100 – 150 of BAMBI.
Host Species: Rabbit
Purification: BAMBI antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 4880-88-0
Product: Vinburnine
Buffer: BAMBI antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BAMBI antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BMP and activin membrane-bound inhibitor homolog
Accession NO.: NP_036474
Protein Ino: 6912534
Official Symbol: BAMBI
Geneid: 25805
Background: BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).
PubMed ID:http://aac.asm.org/content/53/10/4545.abstract
