Product Name: BACH1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: BACH1 antibody can be used for detection of BACH1 by ELISA at 1:1562500. BACH1 antibody can be used for detection of BACH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 82 kDa, 82 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BACH1.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 173952-44-8
Product: SYM2206
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store BACH1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BACH1, BACH-1, AP000240.4
Accession NO.: NP_001177
Protein Ino: 4502353
Official Symbol: BACH1
Geneid: 571
Background: BACH1 is a transcription factor that belongs to the capncollar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.
PubMed ID:http://aac.asm.org/content/53/10/4172.abstract
