Product Name: B4GALT4 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 40 kDa
Immunogen: This B4GALT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from the Central region of human B4GALT4.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 546-88-3
Product: Acetohydroxamic acid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Beta-1,4-galactosyltransferase 4, Beta-1,4-GalTase 4, Beta4Gal-T4, b4Gal-T4, 241-, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4, N-acetyllactosamine synthase, Nal synthase, Lactotriaosylceramide beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, B4GALT4
Accession NO.: O60513
Protein Ino:
Official Symbol: B4GALT4
Geneid: 8702
Background: This gene is one of seven beta-1,4-galactosyltransferase(beta4GalT) genes. They encode type II membrane-bound glycoproteinsthat appear to have exclusive specificity for the donor substrateUDP-galactose; all transfer galactose in a beta1,4 linkage tosimilar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has adistinct function in the biosynthesis of different glycoconjugatesand saccharide structures. As type II membrane proteins, they havean N-terminal hydrophobic signal sequence that directs the proteinto the Golgi apparatus and which then remains uncleaved to functionas a transmembrane anchor. By sequence similarity, the beta4GalTsform four groups: beta4GalT1 and beta4GalT2, beta4GalT3 andbeta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzymeencoded by this gene appears to mainly play a role in glycolipidbiosynthesis. Two alternatively spliced transcript variants havebeen found for this gene.
PubMed ID:http://aac.asm.org/content/53/9/3752.abstract
