Product Name: B2M Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: B2M antibody can be used for detection of B2M by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 13 kDa Observed: 12 kDa
Immunogen: B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M.The immunogen is located within the last 50 amino acids of B2M.
Host Species: Rabbit
Purification: B2M Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1192189-69-7
Product: LX7101
Buffer: B2M Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: B2M antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: B2M Antibody: Beta-2-microglobulin
Accession NO.: NP_004039
Protein Ino: 4757826
Official Symbol: B2M
Geneid: 567
Background: B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
PubMed ID:http://aac.asm.org/content/53/9/4007.abstract
