Product Name: Angiopoietin-1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IHC, WB
Applications: Angiopoietin-1 antibody can be used in ELISA starting at 1 μg/mL, Western Blot starting at 1 μg/mL, and immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Angiopoietin – 1 antibody was raised against amino acids 21-40 from the C-Terminus of Angiopoietin – 1 (Mouse).
Host Species: Rabbit
Purification: Sterile Filtration
Physical State: Liquid
CAS NO.: 29700-22-9
Product: Oxyresveratrol
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ANGPT1, Angiopoietin 1, Angiopoietin-1, AGPT, AGP1, ANG-1, ANG1, KIAA0003
Accession NO.: Q15389
Protein Ino: 12229574
Official Symbol: ANGPT1
Geneid: 284
Background: Angiopoeitin-1 (Ang-1) and Angiopoietin-2 (Ang-2) have importance in the development of the endothelium by regulating tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding, and thus blocks receptor phosphorylation. Ang-1 has a potential fibrinogen-like domain at the carboxyl terminus and coiled-coil regions in the amino terminus. Ang-1 is prominently expressed in the myocardium of atrium and ventricle, mesenchymal and smooth muscle cells surrounding most blood vessels, and lung. In the adult, Ang-1 is also expressed in the heart and liver.
PubMed ID:http://aac.asm.org/content/52/11/4072.abstract
