Product Name: Amyloid-Beta 3 Antibody
Species Reactivity: Bovine, Human, Non-human Primate, Sheep
Tested Applications: ELISA, IHC, WB
Applications: ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: A synthetic peptide corresponding to the N-terminus 3-pyro E start point.
Host Species: Rabbit
Purification: Affinity Purified
Physical State:
CAS NO.: 1393124-08-7
Product: glucagon receptor antagonists-4
Buffer:
Concentration:
Storage Conditions:
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Amyloid-Beta 3-pyr E, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma, A4
Accession NO.: P05067
Protein Ino: 112927
Official Symbol: APP
Geneid: 351
Background: Pyro-glutamic acid truncated amyloid beta 3-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyro E modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-β. Pyro-glutamic acid truncated amyloid beta 3-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established.
PubMed ID:http://aac.asm.org/content/52/11/4057.abstract
