Product Name: Amyloid-Beta 11 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: ELISA , Western (immuno) blotting (in testing), Immunostaining (in testing)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: A synthetic peptide corresponding to the N-terminus 11-pyro E start point.
Host Species: Rabbit
Purification: Affinity Purified
Physical State:
CAS NO.: 27013-91-8
Product: alpha-Hederin
Buffer:
Concentration:
Storage Conditions:
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Amyloid-Beta 11-pyrE, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma, A4
Accession NO.: P05067
Protein Ino: 112927
Official Symbol: APP
Geneid: 351
Background: Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-β. Pyroglutamic acid truncated amyloid beta 11-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established
PubMed ID:http://aac.asm.org/content/52/11/4023.abstract
