Product Name: Alpha synuclein (phospho Ser129) Antibody
Species Reactivity: Bovine, Dog, Mouse, Rat
Tested Applications:
Applications: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, human, mouse, and non-human primate based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 15
Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser129 of alpha synuclein.
Host Species: Rabbit
Purification: Affinity Purified
Physical State: Liquid
CAS NO.: 61012-19-9
Product: Lecirelin
Buffer: 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Concentration:
Storage Conditions: Alpha synuclein antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Alpha-synuclein
Accession NO.: P37377
Protein Ino: 586065
Official Symbol: Snca
Geneid: 29219
Background: Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Mutation of the alpha-synuclein gene is associated with familial forms of PD (Newmann et al., 2002). Recent evidence suggests that phosphorylation of alpha-synuclein at ser129 plays a role in the formation of inclusions in PD (Smith et al., 2005; Masliah et al., 2005).
PubMed ID:http://aac.asm.org/content/52/9/3118.abstract
