Product Name: Aldh5A1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: Aldh5A1 antibody can be used for detection of Aldh5A1 by Western blot at 0.25 – 0.5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 60 kDa Observed: 60 kDa
Immunogen: Aldh5A1 antibody was raised against a 22 amino acid synthetic peptide near the carboxy terminus of the human Aldh5A1.The immunogen is located within the last 50 amino acids of Aldh5A1.
Host Species: Rabbit
Purification: Aldh5A1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1448428-04-3
Product: Selonsertib
Buffer: Aldh5A1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Aldh5A1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Aldh5A1 Antibody: SSDH, SSADH, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1
Accession NO.: NP_733936
Protein Ino: 25777721
Official Symbol: ALDH5A1
Geneid: 7915
Background: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
PubMed ID:http://aac.asm.org/content/52/8/2898.abstract
