Product Name: AZU1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 27 kDa
Immunogen: This AZU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human AZU1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 75-80-9
Product: 2,2,2-Tribromoethanol
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1
Accession NO.: P20160
Protein Ino: 416746
Official Symbol: AZU1
Geneid: 566
Background: Azurophil granules, specialized lysosomes of theneutrophil, contain at least 10 proteins implicated in the killingof microorganisms. The protein encoded by this gene is an azurophilgranule antibiotic protein, with monocyte chemotactic andantibacterial activity. It is also an important multifunctionalinflammatory mediator. This encoded protein is a member of theserine protease gene family but it is not a serine proteinase,because the active site serine and histidine residues are replaced.The genes encoding this protein, neutrophil elastase 2, andproteinase 3 are in a cluster located at chromosome 19pter. All 3genes are expressed coordinately and their protein products arepackaged together into azurophil granules during neutrophildifferentiation.
PubMed ID:http://aac.asm.org/content/53/9/3799.abstract
