Product Name: ATP11B Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, ICC, IF, WB
Applications: ATP11B antibody can be used for detection of ATP11B by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: ATP11B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11B.The immunogen is located within amino acids 290 – 340 of ATP11B.
Host Species: Rabbit
Purification: ATP11B Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 186205-33-4
Product: CY2-SE
Buffer: ATP11B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ATP11B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ATP11B Antibody: ATPIF, ATPIR, ATPIF, KIAA0956, Probable phospholipid-transporting ATPase IF, ATPase IR
Accession NO.: NP_055431
Protein Ino: 62632750
Official Symbol: ATP11B
Geneid: 23200
Background: ATP11B Antibody: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
PubMed ID:http://aac.asm.org/content/53/7/3017.abstract
