Product Name: ASXL1 Antibody
Species Reactivity: Mouse
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100For FACS starting dilution is: 1:10~50For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 165 kDa
Immunogen: This ASXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 116209-55-3
Product: Levobetaxolol (hydrochloride)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978
Accession NO.: Q8IXJ9
Protein Ino: 317373477
Official Symbol: ASXL1
Geneid: 171023
Background: This gene is similar to the Drosophila additional sexcombs gene, which encodes a chromatin-binding protein required fornormal determination of segment identity in the developing embryo.The protein is a member of the Polycomb group of proteins, whichare necessary for the maintenance of stable repression of homeoticand other loci. The protein is thought to disrupt chromatin inlocalized areas, enhancing transcription of certain genes whilerepressing the transcription of other genes. The protein encoded bythis gene functions as a ligand-dependent co-activator for retinoicacid receptor in cooperation with nuclear receptor coactivator 1.Mutations in this gene are associated with myelodysplasticsyndromes and chronic myelomonocytic leukemia. Alternative splicingresults in multiple transcript variants.
PubMed ID:http://aac.asm.org/content/53/6/2306.abstract
