Product Name: ARTS Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: ARTS antibody can be used for detection of ARTS by Western blot at 2 μg/mL. A band at 32 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 32 kDa
Immunogen: ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.The immunogen is located within the first 50 amino acids of ARTS.
Host Species: Rabbit
Purification: ARTS Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 537034-17-6
Product: BML-210
Buffer: ARTS Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ARTS antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ARTS Antibody: H5, ARTS, MART, SEP4, CE5B3, PNUTL2, hucep-7, BRADEION, hCDCREL-2, Septin-4, Apoptosis-related protein in the TGF-beta signaling pathway
Accession NO.: AAG45673
Protein Ino: 12024871
Official Symbol: 42982
Geneid: 5414
Background: ARTS Antibody: Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-α and Fas ligand.
PubMed ID:http://aac.asm.org/content/53/5/2066.abstract
