Product Name: ARRB1 Antibody
Species Reactivity: Human
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50For IF starting dilution is: 1:10~50For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 47 kDa
Immunogen: This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 136765-35-0
Product: Haloperidol (D4)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Accession NO.: P49407
Protein Ino: 20141238
Official Symbol: ARRB1
Geneid: 408
Background: Members of arrestin/beta-arrestin protein family arethought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening ofcellular responses to stimuli such as hormones, neurotransmitters,or sensory signals. Arrestin beta 1 is a cytosolic protein andacts as a cofactor in the beta-adrenergic receptor kinase (BARK)mediated desensitization of beta-adrenergic receptors. Besides thecentral nervous system, it is expressed at high levels inperipheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediatedimmune functions. Alternatively spliced transcripts encodingdifferent isoforms of arrestin beta 1 have been described, however,their exact functions are not known.
PubMed ID:http://aac.asm.org/content/53/5/1868.abstract
