Product Name: ARAP2 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 193 kDa
Immunogen: This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 13419-46-0
Product: DCVC
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1, Protein PARX, ARAP2, CENTD1, KIAA0580
Accession NO.: Q8WZ64
Protein Ino: 308153629
Official Symbol: ARAP2
Geneid: 116984
Background: The protein encoded by this gene contains ARF-GAP,RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homologydomains. The protein is a phosphatidylinositol(3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, butit lacks the predicted catalytic arginine in the RHO-GAP domain anddoes not have RHO-GAP activity. The protein associates with focaladhesions and functions downstream of RhoA to regulate focaladhesion dynamics.
PubMed ID:http://aac.asm.org/content/53/3/1165.abstract
