Product Name: APRIL Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: APRIL can be used for detection of APRIL by Western blot at 5 – 10 μg/mL. A 27 kDa band can be detected.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 27 kDa
Immunogen: APRIL antibody was raised against a synthetic peptide corresponding to amino acids near the center of human APRIL.The immunogen is located within amino acids 50 – 100 of APRIL.
Host Species: Rabbit
Purification: APRIL Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1494675-86-3
Product: DprE1-IN-1
Buffer: APRIL Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: APRIL antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: APRIL Antibody: APRIL, CD256, TALL2, ZTNF2, TALL-2, TRDL-1, UNQ383/PRO715, APRIL, Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand
Accession NO.: NP_003799
Protein Ino: 4507599
Official Symbol: TNFSF13
Geneid: 8741
Background: APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1α (for TNF related death ligand 1α) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
PubMed ID:http://aac.asm.org/content/53/3/1124.abstract
