Product Name: APG4B Antibody
Species Reactivity: Dog, Human, Mouse, Rat
Tested Applications: ELISA, IHC, WB
Applications: APG4B antibody can be used for detection of APG4B by ELISA at 1:312500. APG4B antibody can be used for detection of APG4B by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 44 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APG4B.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1265229-25-1
Product: CH5183284
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store APG4B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: APG4B, APG4B, AUTL1
Accession NO.: NP_037457
Protein Ino: 47132611
Official Symbol: ATG4B
Geneid: 23192
Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
PubMed ID:http://aac.asm.org/content/53/2/756.abstract
