Product Name: APEX Nuclease Antibody
Species Reactivity: Bovine, Dog, Gorilla, Human, Monkey, Pig, Rabbit
Tested Applications: IHC, WB
Applications: APEX Nuclease antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: APEX Nuclease antibody was raised against synthetic peptides of APEX Nuclease (Human).
Host Species: Rabbit
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 853220-52-7
Product: BML-284
Buffer: PBS, 0.02% sodium azide.
Concentration:
Storage Conditions: Store APEX Nuclease antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: APEX2, AP endonuclease 2, AP endonuclease XTH2, APEX nuclease 2, APEX nuclease-like 2, APEXL2, APE2, XTH2
Accession NO.: Q9UBZ4
Protein Ino: 73921676
Official Symbol: APEX2
Geneid: 27301
Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA by spontaneous hydrolysis, DNA damaging agents or DNA glycosylases that remove specific abnormal bases. ClassII AP endonucleases act to repair this damage by cleaving the phosphodiester backbone. It is primarily located in the nucleus but is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).
PubMed ID:http://aac.asm.org/content/53/2/563.abstract
