Product Name: ANXA6 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ANXA6 antibody can be used for detection of ANXA6 by ELISA at 1:312500. ANXA6 antibody can be used for detection of ANXA6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 74 kDa, 75 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA6.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 1268454-23-4
Product: MLN1117
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store ANXA6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ANXA6, ANX6, CBP68
Accession NO.: NP_001146
Protein Ino: 71773329
Official Symbol: Anxa6
Geneid: 309
Background: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
PubMed ID:http://aac.asm.org/content/53/1/81.abstract
