Product Name: ANAPC1 (phospho Ser377) Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC, WB
Applications: ANAPC1 antibody can be used in ELISA starting at 1:000 – 1:1000, and immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: ANAPC1 antibody was raised against phospho amino acids 373-382 of ANAPC1 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 537034-15-4
Product: NKL 22
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration: 1 mg/ml
Storage Conditions: Store ANAPC1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ANAPC1, APC1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24
Accession NO.: Q9H1A4
Protein Ino: 37537845
Official Symbol: ANAPC1
Geneid: 64682
Background: APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.
PubMed ID:http://aac.asm.org/content/52/11/4089.abstract
