Product Name: ANAPC10 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: ANAPC10 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: ANAPC10 antibody was raised against aa 10 – 20 of ANAPC10 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 465-99-6
Product: Hederagenin
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Store ANAPC10 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ANAPC10, Cyclosome subunit 10, DKFZP564L0562, APC10, DOC1
Accession NO.: Q9UM13
Protein Ino: 34395509
Official Symbol: ANAPC10
Geneid: 10393
Background: APC is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds 1/Cut 2 and cyclin B. It was found that APC 10/Doc 1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid body in telophase and cytokinesis. These results strongly support the notion that human APC 10/Doc 1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
PubMed ID:http://aac.asm.org/content/52/11/4115.abstract
