Product Name: AMOTL1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: AMOTL1 antibody can be used for detection of AMOTL1 by ELISA at 1:312500. AMOTL1 antibody can be used for detection of AMOTL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 106 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMOTL1.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 220355-63-5
Product: UKI-1
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store AMOTL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AMOTL1, JEAP
Accession NO.: NP_570899
Protein Ino: 22027646
Official Symbol: AMOTL1
Geneid: 154810
Background: AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
PubMed ID:http://aac.asm.org/content/52/10/3801.abstract