Product Name: ALSFTD Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, WB
Applications: ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 53 kDa Observed: 52 kDa
Immunogen: ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD.The immunogen is located within amino acids 400 – 450 of ALSFTD.
Host Species: Rabbit
Purification: ALSFTD Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 935273-79-3
Product: MK-4101
Buffer: ALSFTD Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ALSFTD antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Amyotrophic lateral sclerosis with frontotemporal dementia, chromosome 9 open reading frame 72, C9orf72
Accession NO.: NP_060795
Protein Ino: 37039612
Official Symbol: ALSFTD
Geneid: 203228
Background: ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).
PubMed ID:http://aac.asm.org/content/52/10/3517.abstract