Product Name: AIM Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IHC-P, WB
Applications: AIM antibody can be used for the detection of AIM by Western blot at 0.5 – 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: AIM antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human AIM.The immunogen is located within amino acids 250 – 300 of AIM.
Host Species: Rabbit
Purification: AIM Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 103222-11-3
Product: Vapreotide
Buffer: AIM Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: AIM antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AIM Antibody: AIM, API6, PRO229, Spalpha, SP-ALPHA, UNQ203/PRO229, CD5 antigen-like, CT-2
Accession NO.: AAD01446
Protein Ino: 4102235
Official Symbol: CD5L
Geneid: 922
Background: AIM Antibody: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
PubMed ID:http://aac.asm.org/content/52/7/2340.abstract
