Product Name: AGTR2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC-P, WB
Applications: AGTR2 antibody can be used for detection of AGTR2 by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 40 kDa Observed: 36 kDa
Immunogen: AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2.The immunogen is located within amino acids 220 – 270 of AGTR2.
Host Species: Rabbit
Purification: AGTR2 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 118374
Product: Asparagusic acid
Buffer: AGTR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: AGTR2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AGTR2 Antibody: AT2, ATGR2, MRX88, Type-2 angiotensin II receptor, Angiotensin II type-2 receptor, AT2
Accession NO.: AAS45437
Protein Ino: 42766665
Official Symbol: AGTR2
Geneid: 186
Background: AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
PubMed ID:http://aac.asm.org/content/52/6/2014.abstract
