Product Name: AFX (Ab 197) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
User Note:
Predicted Molecular Weight: 65 kDa
Immunogen: AFX (Ab-197) antibody was raised against a peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 30034-03-8
Product: Cefamandole (sodium)
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AFX, AFX1, MLLT7, MAPTL, MTBT1, TAU, AFX, FOXO4, Afxh
Accession NO.: NP_001164402.1
Protein Ino: 283436083
Official Symbol: FOXO4
Geneid: 4303
Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
PubMed ID:http://aac.asm.org/content/52/6/2120.abstract