Product Name: ADI1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: MTCBP-1 antibody can be used for the detection of 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 21.5 kDa (calculated)
Immunogen: 1-179
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 1796596-46-7
Product: NSC23005 (sodium)
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: ADI1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: MTCBP1, HMFT1638, 1, 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, ARD, APL1, SIPL, mtnD, Fe-ARD, MTCBP1, Ni-ARD, Aci-reductone dioxygenase, Submergence-induced protein 2, ADI1 antibody
Accession NO.: NP_060739.1
Protein Ino: 8922762
Official Symbol: ADI1
Geneid: 55256
Background: FUNCTION: Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.SUBUNIT: Interacts with MMP14.SIMILARITY: Belongs to the acireductone dioxygenase (ARD) family.COFACTOR: Binds 1 nickel ion per monomer. Can also use other divalent metal cations (By similarity).
PubMed ID:http://aac.asm.org/content/52/4/1345.abstract
