Product Name: AADAT Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC-P
Applications: ELISA: antibody detection limit dilution 1:32000. Immunohistochemistry: In paraffin embedded Human Kidney shows mitochondrial staining in PCT. Recommended concentration, 2-4μg/ml.
User Note:
Predicted Molecular Weight:
Immunogen: AADAT Antibody was raised against synthetic peptide DRVIDFYSNQKD found at an internal region of AADAT.
Host Species: Goat
Purification: AADAT Antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 10030-78-1
Product: N2-Methylguanine
Buffer: AADAT is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AADAT, aminoadipate aminotransferase, KAT2, KATII, L kynurenine/alpha aminoadipate aminotransferase, L-kynurenine/alpha-aminoadipate aminotransferase, alpha-aminoadipate aminotransferase, kynurenine aminotransferase II
Accession NO.: NP_057312.1, NP_872603.1
Protein Ino: 7705897
Official Symbol: AADAT
Geneid: 51166
Background:
PubMed ID:http://aac.asm.org/content/51/11/3824.abstract
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Product Name: AADAT Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: AADAT antibody can be used for detection of AADAT by ELISA at 1:1562500. AADAT antibody can be used for detection of AADAT by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 47 kDa, 47 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AADAT.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 1391426-24-6
Product: Lys01 (trihydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store AADAT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AADAT, KAT2, KATII
Accession NO.: NP_057312
Protein Ino: 7705897
Official Symbol: AADAT
Geneid: 51166
Background: AADAT is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties.This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
PubMed ID:http://aac.asm.org/content/51/11/3895.abstract