Product Name: A2BP1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: A2BP1 antibody can be used for detection of A2BP1 by ELISA at 1:62500. A2BP1 antibody can be used for detection of A2BP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 40 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A2BP1.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1437321-24-8
Product: CEP-40783
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store A2BP1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: A2BP1, 2BP1, FOX1, A2BP1, FOX-1, HRNBP1
Accession NO.: NP_001135805
Protein Ino: 215272410
Official Symbol: RBFOX1
Geneid: 54715
Background: Ataxin-2 binding protein 1 (A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
PubMed ID:http://aac.asm.org/content/51/11/4205.abstract
